SS-31 (Elamipretide)

Overview
SS‑31 (also known as Elamipretide or MTP‑131) is a synthetic tetrapeptide widely utilized in in vitro and laboratory‑based research involving mitochondrial structure, bioenergetics, and oxidative‑stress response pathways. It is of particular interest for studies examining peptide interactions with cardiolipin, a phospholipid located within the inner mitochondrial membrane, and its role in mitochondrial stability and function.
Molecular Characteristics
Peptide Type: Mitochondria‑targeting tetrapeptide analog
Form: Lyophilized powder
Purity: ≥ 98% (HPLC)
Storage: –20°C recommended
Research Applications
SS‑31 is commonly investigated in controlled laboratory environments for:
Cardiolipin‑binding studies
Mitochondrial membrane‑stability analysis
Assay development involving oxidative‑stress pathways
In vitro modeling of bioenergetic regulation
Biochemical exploration of mitochondrial efficiency under stress conditions
 
Mechanistic Notes (Research Context Only)
In laboratory settings, SS‑31 is studied for its interaction with:
Cardiolipin‑associated membrane structures
Mitochondrial cristae‑stability mechanisms
Reactive oxygen species (ROS)–related biochemical pathways
Cellular energy‑regulation models
These statements describe mechanistic interest, not biological effects in humans or animals.
Storage & Handling
Store lyophilized peptide at –20°C
Avoid repeated freeze–thaw cycles
Handle reconstituted solutions according to laboratory best practices
Important Research Notice
For laboratory research use only
Not for human consumption
Not a drug, food, or cosmetic
Not for veterinary or household use
No medical or therapeutic claims are made