MOTS-C

Overview
MOTS‑C (Mitochondrial Open Reading Frame of the 12S rRNA type‑C) is a 16‑amino‑acid peptide encoded by mitochondrial DNA. It is widely utilized in in vitro and laboratory‑based research focused on metabolic regulation, mitochondrial signaling, and cellular stress‑response pathways. MOTS‑C is of particular interest for studies involving AMPK‑related biochemical mechanisms.
Molecular Characteristics
Peptide Type: Mitochondrial‑derived peptide analog
Form: Lyophilized powder
Purity: ≥ 98% (HPLC)
Storage: –20°C recommended
Research Applications
MOTS‑C is commonly investigated in controlled laboratory settings for:
AMPK pathway analysis
Cellular energy‑regulation studies
Mitochondrial signaling research
Assay development involving metabolic stress responses
In vitro modeling of nutrient‑sensing pathways
 
Mechanistic Notes (Research Context Only)
In laboratory environments, MOTS‑C is studied for its interaction with AMPK‑related signaling pathways, enabling controlled research on:
Cellular energy‑balance mechanisms
Mitochondrial efficiency and stress‑response pathways
Metabolic regulation under varying nutrient conditions
These statements describe mechanistic interest, not biological effects in humans or animals.
Storage & Handling
Store lyophilized peptide at –20°C
Avoid repeated freeze–thaw cycles
Handle reconstituted solutions according to laboratory best practices
Important Research Notice
For laboratory research use only
Not for human consumption
Not a drug, food, or cosmetic
Not for veterinary or household use
No medical or therapeutic claims are made