FOXO4-DRI (Forkhead Box O4-D-Retro-Inverso) is a cell-penetrating peptide engineered to disrupt the interaction between the transcription factor FOXO4 and the tumor suppressor protein p53. This disruption triggers apoptosis in senescent cells—those that have stopped dividing but resist death—while sparing healthy cells. FOXO4-DRI is at the forefront of senolytic research, offering a promising strategy for age-related dysfunction and tissue rejuvenation.
Key Benefits:
Senescent Cell Clearance: Induces programmed cell death in aging or damaged cells, improving tissue function.
Anti-Aging Potential: Studied for its ability to restore youthful cellular environments and delay biological aging.
Tissue Regeneration: Enhances recovery in models of organ damage and chronic inflammation.
Cancer & Longevity Research: Explored for its role in modulating cell cycle checkpoints and immune surveillance.
🔬 Research Use Only:
This product is intended for Research purposes only.