Overview
FOXO4‑DRI (Forkhead Box O4‑D‑Retro‑Inverso) is a synthetic peptide designed to support in vitro and laboratory‑based research involving protein–protein interactions, cellular stress‑response pathways, and transcription‑factor regulation. It is widely utilized in studies examining the interaction between FOXO4 and p53, enabling controlled exploration of pathways associated with cellular senescence and longevity‑related biochemical mechanisms.
Molecular Characteristics
Peptide Type: FOXO4‑derived retro‑inverso analog
Form: Lyophilized powder
Purity: ≥ 98% (HPLC)
Storage: –20°C recommended
Research Applications
FOXO4‑DRI is commonly investigated in controlled laboratory environments for:
FOXO4–p53 interaction studies
Cellular senescence pathway analysis
Assay development involving stress‑response mechanisms
In vitro modeling of transcription‑factor regulation
Biochemical exploration of longevity‑associated signaling pathways
(All framed as research domains, not biological outcomes.)
Mechanistic Notes (Research Context Only)
In laboratory settings, FOXO4‑DRI is studied for its ability to:
Interact with FOXO4 and p53‑related pathways
Support research on cellular stress‑response mechanisms
Enable modeling of senescence‑associated biochemical processes
Facilitate exploration of protein‑binding disruption mechanisms
These statements describe mechanistic interest, not biological effects in humans or animals.
Storage & Handling
Store lyophilized peptide at –20°C
Avoid repeated freeze–thaw cycles
Handle reconstituted solutions according to laboratory best practices
Important Research Notice
For laboratory research use only
Not for human consumption
Not a drug, food, or cosmetic
Not for veterinary or household use
No medical or therapeutic claims are made