Overview
PT‑141 (Bremelanotide) is a cyclic heptapeptide derived from the melanocortin analog Melanotan II. It is widely utilized in in vitro and laboratory‑based research involving melanocortin receptor pathways, central nervous system signaling, and peptide‑mediated neuromodulation. PT‑141 is of particular interest for studies examining MC3R and MC4R receptor activity and their associated biochemical signaling mechanisms.
Molecular Characteristics
Peptide Type: Melanocortin receptor agonist analog
Form: Lyophilized powder
Purity: ≥ 98% (HPLC)
Storage: –20°C recommended
Research Applications
PT‑141 is commonly investigated in controlled laboratory environments for:
Melanocortin receptor (MC3R/MC4R) binding studies
Central nervous system signaling pathway analysis
Assay development involving neuromodulatory peptides
In vitro modeling of melanocortin‑related biochemical processes
Exploration of peptide‑mediated regulatory mechanisms in CNS pathways
Mechanistic Notes (Research Context Only)
In laboratory settings, PT‑141 is studied for its interaction with:
MC3R and MC4R receptor pathways
CNS‑associated neuromodulatory signaling
Biochemical mechanisms related to melanocortin‑regulated pathways
These statements describe mechanistic interest, not biological effects in humans or animals.
Storage & Handling
Store lyophilized peptide at –20°C
Avoid repeated freeze–thaw cycles
Handle reconstituted solutions according to laboratory best practices
Important Research Notice
For laboratory research use only
Not for human consumption
Not a drug, food, or cosmetic
Not for veterinary or household use
No medical or therapeutic claims are made